La metformine réduit de 40% le risque de “covid long” chez les personnes en surpoids ou obèses.

La metformine réduit de 40% le risque de “covid long” chez les personnes en surpoids ou obèses.

Fatigue intense, dysfunction du système neurologique, troubles cognitifs, difficultés respiratoires, troubles sensoriels… Le “covid long” is defined by the presence of symptoms that persist for more than three months after an acute infection with Sars-Cov2. “A situation that can have a significant impact on daily life,” explain scientists from the University of Minnesota. Who have sought to determine whether it is possible to prevent this prolonged form of the disease.

A 40% reduction

The researchers recruited over 1,200 overweight or obese individuals, aged 30 to 85. Each received – at random – either metformin (a well-known medication for treating type 2 diabetic patients), ivermectin (an antiparasitic), fluvoxamine (an antidepressant), or a placebo.

After ten months, 35 participants who took metformin received a diagnosis of long Covid, compared to 58 in the placebo group – a 40% reduction in risk. Ivermectin and fluvoxamine, on the other hand, showed no effect. “Metformin is an inexpensive, safe, and widely available medication,” explains Carolyn Bramante, author of the study. “Its use as a preventive measure could have significant implications for public health.”

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